In patients with heart failure, the pressure of the atrium and ventricular wall increases, and the cardiomyocytes will secrete proteins, and the protein is then cut into several segments, one of which can play a role in diuresis, dilating blood vessels, reducing the load on the heart, and is protective, and part of the other segments is called NT-ProBNP, generally active protein is called BNP, and inactive protein is called NT-ProBNP.