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CMV Uncut Sheet

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Disease Type:

Infection with CMV in the population is very common, but it is mostly subclinical recessive and latent infection, and when the infected person is immunocompromised or pregnant, receives immunosuppressant therapy, organ transplantation, and has tumors, the virus can be activated to cause clinical symptoms. After human cytomegalovirus infection in pregnant women, the virus infects the fetus through the placenta, causing an intrauterine infection. Therefore, CMV-IgM antibody detection is of great significance for understanding the status of human cytomegalovirus infection in women of childbearing age, early diagnosis of congenital human cytomegalovirus infection, and prevention of the birth of congenital infected children.

CMV Uncut Sheet

 

Cytomegalovirus is a herpesvirus group DNA virus. Also known as cellular inclusion virus, it is due to the enlargement of infected cells and has large intranuclear inclusion bodies. CMV has a typical herpesvirus morphology, and its DNA structure is also similar to HSV, but 5% larger than HSV. Detection of lgM antibodies and lgG antibodies with ELISA is suitable for early infection and epidemiological investigation. IgG antibodies persist for life, and lgM antibodies are associated with acute infection.

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