Urinary microalbumin(mALB) assay reflects early nephropathy and renal injury. Pathological increase was seen in diabetic nephropathy, hypertension, and preeclampsia. In the early stage of urinary microalbumin(mALB) stage is the early signal and omen of the occurrence of kidney disease, at this time the kidney damage is in the reversible period, such as timely treatment, can terminate or reverse the development of kidney disease.