Infection with CMV in the population is very common, but it is mostly subclinical recessive and latent infection, and when the infected person is immunocompromised or pregnant, receives immunosuppressant therapy, organ transplantation, and has tumors, the virus can be activated to cause clinical symptoms. After human cytomegalovirus infection in pregnant women, the virus infects the fetus through the placenta, causing an intrauterine infection. Therefore, CMV-IgM antibody detection is of great significance for understanding the status of human cytomegalovirus infection in women of childbearing age, early diagnosis of congenital human cytomegalovirus infection, and prevention of the birth of congenital infected children.